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Energies 17 , 1164 (2024)

Although it is currently not clear if tamoxifen is effective in targeting other types of drug resistant cells that over-express P-gp, based on our current understanding of the mechanism of collateral sensitivity of P-gp-overexpressing cells, we speculate that tamoxifen alone or in combination with rotenone could reduce the rise of drug resistant tumor cells

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Farris P

In this coordinated system, GSH provides rapid copper sequestration and distribution capacity, whereas certain MTs serve as high-affinity copper reservoirs that limit metal toxicity