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Role of the Nrf2 pathway and ferroptosis in lung cancer Keap1-Nrf2-FSP1-mediated ferroptosis in lung cancer Studies on non-small cell lung cancer (NSCLC), both preclinical and clinical, have demonstrated tight relationships among the resistance to chemotherapy, radiation therapy, and other agents, and the loss of function of Keap1 and overexpression of Nrf2

doi:10.1111/j.1467-2494.2005.00235.x 32

Wu Q, Zhao X, Bai Y, Sun B, Xie Q, Ma J (2017) The first identification and complete genome of senecavirus A affecting pig with idiopathic vesicular disease in China

Metalloporphyrins contain Mn or Fe metals coordinated by four donor nitrogens in a square planar arrangement and have been reported to scavenge superoxide radicals (O 2 ) (Pasternack and Skowronek 1979), hydrogen peroxide (H 2 O 2 ), peroxynitrite (ONOO ) and hydroperoxides (LOOH) (Day et al