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382,383 IL-6 signaling pathway The IL-6/STAT3 signaling pathway is critical for cellular responses in the early stage of liver regeneration

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In a case-control study involving smokers with normal lung function, COPD, and lung cancer (COPD subtype), it was found that the GG genotype of the rs1489759 HHIP SNP and the CC genotype of the rs2202507 GYPA SNP exhibited a protective effect against both COPD (OR 0.59, p = 0.006 for HHIP and OR = 0.65, p = 0.006 for GYPA) and lung cancer (OR = 0.70, p = 0.05 for HHIP and OR = 0.70, p = 0.02 for GYPA) [139]

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By regulating the expression of these transporters, MTF-1 can control the influx and efflux of zinc across the cell membrane and within the cell, further contributing to the maintenance of zinc homeostasis [141, 142]