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Activated Wnt/-catenin further promotes the expression of Jag1 in PCECs, stimulating Notch signalling in fibroblasts and enhancing fibrosis

Our peptide reconstitution guide covers the mechanics of how vial volume, peptide mass, and diluent volume determine final concentration, and why the diluent has to physically fit the vial

Wu applied this metric to six TrialNet studies and found that extrapolating TMRCP identified the same treatments as effective as each original analysis

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Optimization included testing the inclusion of gp42 alone or with gp350, the effect of the order of the two glycoproteins gH and gL in tandem expression constructs, the timing and dosing of repRNA delivery, the effect of soluble versus membrane-anchored antigen, and the delivery of gH/gL fused to different multimeric constructs encoded by repRNA