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10.1021/acsomega.8b03590 36 ChudasamaY.WrightK

[92] Drug design and drug development exploits NAD + in three ways: as a direct target of drugs, by designing enzyme inhibitors or activators based on its structure that change the activity of NAD-dependent enzymes, and by trying to inhibit NAD + biosynthesis

These findings highlight the coordinated passage of the viral capsids across the two nuclear membranes