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Collagen contains a number of hydroxylated prolines and lysines that are needed for collagen strands to properly cross-link

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10.1016/j.it.2021.05.004 90 QianY.GuanT.HuangM.CaoL.LiY.ChengH.et al (2012)

For instance, mechanical disruption of the BBB facilitates the infiltration of blood-borne molecules and contributes to ROS production and proinflammatory mediator release, which further compromise BBB integrity

SAC treatment markedly reduced ROS levels, restored GSH levels, and attenuated MDA accumulation, demonstrating its efficacy in alleviating oxidative stress and lipid peroxidation in UC mice