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However, studies have found that abnormal activity of the HPA axis, such as excessive activity or persistent disorder, is closely related to the development of depression (Nelson and Davis, 1997

New Journal of Chemistry 41 , 54125419, (2017)

Mutations in genes such as SOD1, TDP-43, and FUS lead to the formation of toxic protein aggregates specifically within motor neurons

Phytosterols (PS) inhibit AGE formation by interacting with the lysine residues of bovine serum albumin (BSA), preventing the binding of reducing sugars to proteins (100)