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At moderate levels, ROS support tumorigenic processes including proliferation, angiogenesis, and therapy resistance [14,15,16]

La baisse du GSH est la fois une consquence et un amplificateur du vieillissement : l'accumulation de dommages oxydatifs rduit la capacit de synthse, tandis que la dpltion en glutathion laisse les cellules plus vulnrables aux agressions suivantes