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Age, family history, and the presence of the apolipoprotein E 4 allele have been found to be significant risk factors for the development of Alzheimer disease and all-cause dementia.1-3 More recently, a high plasma concentration of homocysteine has also been shown to be a risk factor for Alzheimer disease and dementia.4 Docosahexaenoic acid (DHA), an -3 polyunsaturated fatty acid found in some foods and many tissues in the body, also appears to be important in affecting the risk of dementia

Although they are approximately 2.5 times more frequent in females, similar to AIP -associated cases, they pose a greater therapeutic challenge in males (227)

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This process is crucial for the downstream effects that result in growth hormone release

Leung, W