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Janus kinase/signal transducer and activator of transcription signaling Another mechanism for GH resistance in uremia is a defect in post-receptor GH-activated Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling (Fig

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doi: 10.1016/j.cell.2015.05.025 101 OberkampfMGuillereyCMourisJRosenbaumPFayolleCBobardAet al