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If it is assumed that neutralization is the dominant protective mechanism, then for some viruses, animal models or challenge routes, it may be necessary for antibody to neutralize essentially every virus particle to achieve protection, which would require an excess of antibody

Baicalin prevents myocardial ischemia/reperfusion injury through inhibiting ACSL4 mediated ferroptosis

Nature Fabio Hecht et al

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While both the N-terminal and C-terminal regions of ATG2 exhibit affinity for membranes, studies conducted in cellular contexts suggest that the function of the N-terminal region is linked to its interaction with the ER, whereas the C-terminal amphipathic helix plays a crucial role in directing ATG2A to phagophores and lipid droplets (Tamura et al, 2017