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Some of the mimetics are BBB permeable, orally active, and display profound PD therapeutic as well as pro-cognitive/anti- dementia activity

In hypoxic tumor microenvironments, hypoxia inducible factor 1 subunit alpha (HIF1A, also known as HIF1) represses DLAT expression and confers resistance to cuproptosis 176 , supporting the existence of a HIF1A-DLAT-GSH regulatory axis

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