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Core Molecular Pathways Driving Ferroptosis Ferroptosis is a regulated form of cell death defined by iron dependent lipid peroxidation. Its execution requires the convergence of iron metabolism, oxidative stress, and polyunsaturated lipid remodeling Antioxidant Enzymes in Cancer Cells: Their Role in Photodynamic Therapy Resistance and Potential as Targets for Improved Treatment Outcomes Steroid Sulfatase an overview ScienceDirect Topics Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Upregulation of ferroptosis in glucocorticoids induced posterior subcapsular cataracts Communications Biology

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