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doi: 10.1111/j.2042-3306.2012.00623.x

Sulfation (Safe Pathway) DECREASES 33% The Brookhuis 2021 data showed: The estimated molar dose fraction of acetaminophen-sulphate decreased with the duration of pregnancy (24.2 (22.326.2%), 21.5 (19.923.1%) and 20.7 (19.122.4%) in the first, second and third trimester, respectively) compared with non-pregnant women (31.1 (29.033.3%)).[] **This is a 33% DECREASE in the safe sulfation pathway by third trimester** (20.7% vs 31.1%)

Nunley PD, Shamie N, Blumenthal SL, Orndorff D, Block JE, Geisler FH: Interspinous Process Decompression: Expanding Treatment Options for Lumbar Spinal Stenosis