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This is particularly relevant for people taking weight loss injections, such as GLP-1 agonists (e.g., Ozempic or Mounjaro), which can sometimes cause fatigue and a feeling of low energy

To date, no human clinical trials have been completed, and all published efficacy data come from controlled murine studies using intraperitoneal injection

b , The alternation of surface mainly derived from an outstanding conformational change of the loop between Pro124 and Ala133, with which the side chains of Arg152 formed multiple hydrogen bonds in the wild-type, but not His152 in the mutant

doi: 10.1186/2045-824X-3-15 30 ZeglinskiMRGranvilleDJ