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Common ions, like zinc (Zn 2+ ), magnesium (Mg 2+ ), iron (Fe 2+ /Fe 3+ ) and copper (Cu 2+ ), are co-factors of a variety of enzymes which play an important role in stabilizing enzyme conformation, transferring electrons, and connecting enzymes and substrates in enzymatic reactions (Valdez et al., 2014)

S -dichlorovinyl, such as N -acetyl- S -(1,2-dichlorvinyl)-L-cysteine and S -(1,2-dichlorovinyl)-L-cysteine, induce toxicity towards the cells responsible for their production (Spencer and Schaumburg, 1985

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This work was partially supported by the National Natural Science Foundation (31770796 to Y.J., 81730099 to X.X.), the National Science and Technology Major Project (2018ZX09711002-002-002) to Y.J., the National Key R&D Programs of China (2018YFA0507002), the Shanghai Municipal Science and Technology Major Project (2019SHZDZX02), the CAS Strategic Priority Research Program (XDB37030103) to H.E.X., and the Shanghai Municipal Science and Technology Commission Grant (20S11903200) to X.X