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Int J Oncol

A possible explanation may be the large inter-individual difference in biliary B 12 excretion

Primabalt: Often available as methylcobalamin or hydroxocobalamin

For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist

When to increase dose Consider increasing if: Minimal response after 4-6 weeks at current dose No side effects at current dose Current dose below the higher end of recommended range Goals not being met with conservative approach Increase gradually, typically by 25-50% at a time