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63 Building on this approach, Pathway-Level Information Extractor (PLIER) further integrates biological priors, such as pathway and marker gene sets, to improve interpretability and separate biological variation from technical noise particularly valuable for aging muscle tissue, in which subtle transcriptomic shifts are challenging to resolve

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However, the absence of further reduction products than tetrahydrocurcumin (THC) indicates that catalytic reduction by CurA is only effective for compounds with C = C double bonds ( Health benefits and biological impacts of curcumin As seen in Table 3 and Figure 4, curcumin has many different impacts on human health

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