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Indirectly, ROS clearance is facilitated through the inhibition of the NF-B pathway, which consequently downregulates the expression of inflammatory mediators and cytokines, such as tumor necrosis factor-alpha (TNF-) and interleukin-8 (IL-8)

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Thus, adolescent alcohol exposure may lead to psychopathology associated with reduced NPY and BDNF in adulthood via DNA methylation of Npy and Bdnf (4042)

2 Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects Harris et al (2013)

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