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The duration, timing, and cyclic-nature of pineal melatonin production, as well as its seasonal variation according to photoperiod changes, contribute to the temporal organization of physiological phenomena into circadian and circannual timescales ( eigen-zeitgeber action (i.e., being an internal temporal cue) or seasonal effect resulting from these sources

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Front Immunol (2023) 14:1288879

In order to ensure the highest quality of the product, laboratory tests for concentration and purity, which can be found in the Studies tab, are carried out for each batch of the product