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Since mice did not show changes in the density of any cell type, the authors suggested that the KD caused no brain damage

NAC discussion gets really interesting

The results indicated that scaffold implantation helps maintain intervertebral disc height, reduces NP moisture loss, and partially restores the biomechanical function of the IVD ( In vitro and in vivo experiments demonstrated that this composite scaffold enhanced osteogenic differentiation, promoted angiogenesis, and accelerated abnormal NP degeneration, making it suitable for lumbar interbody fusion (Zhang et al., 2025b)

If FDA follows a positive PCAC recommendation and completes rulemaking, 503A pharmacies will have a legal pathway to compound these substances for individual patients