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Adverse events occurring in patients during the study period (113 patients)

Therefore, further studies are needed to identify drugs that can effectively regulate COX-2 or PGE2 and are better for use against parasites

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161 SatohT.KosakaK.ItohK.KobayashiA.YamamotoM.ShimojoY.et al (2008)

This extension of gap bonds during in vitro maturation in the presence of PDE4 inhibitors could allow passage of metabolites, ions, nucleotides and amino acids, which improve oocyte cytoplasm maturation, bringing it near synchronization of nuclear and cytoplasmic maturation, which would favor blastocyst production and quality