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Theyve also noticed an association between the MTHFR mutation and psychiatric disorders and neurological diseases like depression, autism spectrum disorder, Parkinsons disease and Alzheimers disease.[2] Because methylfolate is involved in DNA repair and replication, and it plays an important role in glutathione production and detoxification, an MTHFR mutation might also be associated with higher cancer risk

doi: 10.1016/j.jnutbio.2022.109215 52 AponteMMurruNShoukatM