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31 NAC combined with vitamins A and E plus essential fatty acids is also highly effective in reducing reactive oxygen species which has been shown to improve pregnancy rate

FP was calculated by measuring perpendicular and parallel fluorescence intensity values using the excitation and emission wavelengths of 482 nm and 530 nm, respectively, in a CLARIOstar microplate reader (BMG Labtech)

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SOD2) ( 2 O 2 , producing H 2 O and O 2 ( Intrinsic apoptosis is a form of programed cell death (RCD) initiated by a variety of microenvironmental perturbations, including (but not limited to) growth factor withdrawal, DNA damage, endoplasmic reticulum (ER) stress, reactive oxygen species (ROS) overload, replication stress, microtubular alterations, and mitotic defects ( Intrinsic apoptosis (type I cell death) ( Bcl-2 family proteins are subdivided into three groups on the basis of their pro- or anti-apoptotic action and Bcl-2 homology (BH) domains ( The mechanisms for the activation of pro-apoptotic Bcl-2 family members, such as Bax and Bad, have been well-studied

Cai J, Wallace DC, Zhivotovsky B, Jones DP