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Such findings highlight diet as a powerful modulator of epigenetic regulation

In line with our results, these studies underscore the importance of the inclusion of microglia in recapitulating HIV-induced neuroinflammation, although the data linking to immunometabolic dysregulation is limited

Clinical characteristics regarding individual OBS components are shown in Table 3

For example, indoleamine 2,3-dioxygenase (IDO), which can degrade tryptophan and inhibit immune responses [298], has been explored in several clinical studies, which we will describe below