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This inhibition is achieved by reducing stromal cell-derived factor 1 alpha (SDF1) released by CAFs, thereby augmenting the anti-tumor effect of EGFRvIII targeted CAR-T therapy [770]

Cyanocobalamin is indicated for vitamin B 12deficiencies due to malabsorption which may be associated with the following conditions: It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue

The LOD was reported to be 115 nM with a detection range from 0.333 to 66.6 M

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