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It is thought to interact with beta-3 adrenergic receptors, which are involved in regulating fat metabolism

28 Co-occurring conditions like anxiety, depression, stress, and sleep disorders can be contributors, while disturbances that are difficult to diagnose, such as dysregulated stress reactivity, neurotransmitter imbalance, inflammation, mitochondrial dysfunction, free radical damage, hormonal imbalance, and metabolic disturbance, as well as crosstalk between these factors, may also play a role

Koheler, R

In terms of population acceptability, Wong et al

Cagrilintide on its own led to an average of 11.8% body weight reduction over 68 weeks