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The mutated Htt protein forms protein aggregates leading to neuronal damage and disrupt many critical cellular functions in the striatum and cerebral cortex [199]

2014;100 Suppl 1(1):378s85s

The invention provides methods of selecting an antibody capable of selectively binding to an antigen, the methods comprising the following steps: (a) providing an array comprising a plurality of polypeptides, wherein each polypeptide is immobilized to a discrete and known spot on a substrate surface to form an anay of polypeptides, wherein the plurality of polypeptides comprise a sample (e.g., a subset) of antigen binding sites expressed by an individual

For others, the spots may be larger and stretch across the entire nail plate