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Description

Discrepant Se status in cancer and diabetes is thought to be associated with systemic inflammatory status and insulin resistance [77, 78]

Biochim Biophys Acta BBA - Proteins Proteomics

J Thorac Cardiovasc Surg 165(5):1731-1740.e5, 2023

If the abovementioned is occurring, it could mean that IGF-1 administration could also lower glucose levels by suppressing hepatic gluconeogenesis, as well as improving insulin signalling in this organ, leading to IGFBP-1 suppression and overall improvement of the IGF-1/GH/insulin axis