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doi:10.1080/07315724.1997.10718644 Griffith RS, Walsh DE, Myrmel KH, Thompson RW, Behforooz A

Due to the size and fragility of these peptides, GLOW must be administered via subcutaneous injection for optimal absorption and therapeutic effect

Thus, it prevents the activation of pain and migraine networks in the brain, including disruption of CGRP activity , which has become a central focus in most of the new migraine medications on the market such as the gepants and CGRP monoclonal antibodies

Have not had any issues what so ever with them

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