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Prx5 is a peroxidase that can use cytosolic or mitochondrial Trx to reduce alkyl hydroperoxides or peroxynitrite with high rate constants, whereas its reaction with H 2 O 2 is modest (Knoops et al., 2011)

First, aspartic acid is converted via -aspartyl-semialdehyde into homoserine, introducing the pair of contiguous methylene groups

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The model includes a multifactorial intervention on improving diet, exercise, environmental adaptations, hip protectors, osteoporosis medications, and medication reviews to treat residents at high risk of fracture