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Main Hormonal Regulators of SomatotrophsGHRH and Somatostatin Two brain (hypothalamus)derived modulating factors, the stimulator GHRH and the inhibitor somatostatin (70), act as the primary central regulators of both synthesis and secretion of pituitary GH ( Figure 1 ) (1, 7, 14, 15, 20, 21, 26, 34, 38)

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doi: 10.1038/s41574-018-0096-z 105 LatourteAJaulerrySCombierACherifiCJouanYGrangeTet al