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Their results indicated that, due to the constraint imposed by olfactory axonal diameter, the optimal particle size for nano-drug delivery systems transported along the olfactory pathway should be approximately 100 nm

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Omega-3 fatty acids have been recognized as one of the potential nutritional interventions for cachexia due to their anti-inflammatory and metabolic modulating effects (69, Clinical trials and meta-analyses provide support for the effect of omega-3 in alleviating cachexia

The deficit in ISC enzymes and increase in iron levels were not paired with an increase in ROS in the MCK-KO mouse (Seznec et al., 2005), in Fxn Alb mice with specific depletion of Fxn in liver (Martelli et al., 2015), and in the inducible and reversible FRDAkd mouse model (Chandran et al., 2017)

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