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[PubMed: 26331550] 115

By contrast, AOD-9604s human data are limited: six studies with 893 participants and little or no long-term efficacy or safety data beyond six months, so its role in lasting weight control is uncertain

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It is worth noting that unlicensed medicines can be lawfully supplied in limited circumstances for example, as 'specials' manufactured to meet the specific clinical needs of an individual patient under a prescriber's direction

Since Ruminiclostridium 6 was only observed in the LD control group, it was unsurprising that its relative abundance was significantly greater in this group compared to all other experimental groups (Supplementary Fig