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Dynamic lterations in the ut icrobiota of ollagen-nduced rthritis ats ollowing the rolonged dministration of otal lucosides of aeony

Activated MAPKs phosphorylate downstream targets, resulting in the creation of inflammatory mediators and modifications in tight junction protein expression

If peripheral indices parallel central metabolic defects, and perhaps also neuromorphometric and/or neuroimaging findings, then there exists the possibility that alterations in peripheral indices on longitudinal follow-up (repeated measures) can usefully reflect central membrane function over the course of illness

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Mayatepek E, Nezu J, Tamai I, Oku A, Katsura M, Shimane M, Tsuji A: Two novel missense mutations of the OCTN2 gene (W283R and V446F) in a patient with primary systemic carnitine deficiency