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Additionally, a profound decline in FBS, insulin, and HOMA-IR ( p = 0.014, 0.051, 0.024, respectively) and an increment in QUICKI ( p = 0.019) were observed in the L-carnitine + synbiotic group compared with the L-carnitine + placebo group post-intervention, which remained significant after adjustment for the baseline levels and possible confounding factors

The Wt+R+V mice had significantly higher levels of AGEs (10.95 0.88 SEM) in the midbrain compared to both healthy controls (3.37 0.67 SEM, p = 0.002) and Wt+R+E (5.88 1.02 SEM, p = 0.02) (Fig

Step 6: Confirm Regulatory Compliance A final layer of confidence comes from checking that the product and its importer sit inside Pakistans formal regulatory framework

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