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aureus frequently observed on the skin of AD patients, is associated with the generation of ROS through bacterial enzymes binding to the aryl hydrocarbon receptor (AHR) (40)

By tagging a protein of interest with GST and using it to pull down potential binding partners from a cell lysate, scientists can identify proteins that may serve as targets for therapeutic intervention

Our study suggests that this might be the case for the TARDBP -family, in fact low total glutathione is a feature of patients cells that is shared with family controls (both mutation carrier and non-carrier)

Meszaros, B., Erdos, G