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After 8 to 12 weeks of daily use, you have two options

The rationale for stacking GHK-Cu vs NAD+ together is additive rather than synergistic: GHK-Cu handles structural repair while NAD+ handles bioenergetics

A 2016 study published in Nature Scientific Reports directly compared copper compounds and found that while copper chloride and copper acetate were highly cytotoxic, GHK-Cu showed no cytotoxicity across all tested concentrations and did not induce inflammatory markers