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Description

Skeletal and cardiac muscle cell membranes exhibit greater resistance to PLA 2 , although both crude venom and melittin exert toxic effects on the cardiovascular system

Dietary TMAO precursors such as L-carnitine and choline increased artery hardening in atherosclerosis-prone mice

Chronic metabolic stress induces beta cells to adopt a senescence-associated secretory phenotype (SASP), characterised by cytokines and ECM remodelling factors, that spreads into the surrounding environment promoting beta cell failure [57]