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Furthermore, enhanced permeability of the blood-brain barrier is a critical neurovascular complication of T2DM, which disrupts CNS homeostasis and impairs its function

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10.3390/antiox10101503 40 LnonM.KeN.SzadyC.SakhtahH.RenG.MantaB.et al (2020)

On the other hand, genes such as CCK, CCKAR, CCKBR, DRD1, DRD2, DRD3, DRD4, DRD5, GRIN2A, GRIN2B, HCRT, HOMER1, LMO3, and OPRM1 are known as mechanistic genes whose products can influence the efficacy and safety of L-dopa (Cacabelos et al

As their count surges, the rigidity of hair fibres intensifies concurrently (Gniadecka et al