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These subsequent experiments showed that this nanoinhibitor effectively reduced glioma cell proliferation and invasion in an in vitro model by blocking MET signaling at significantly reduced levels of phosphorylated MET (p-MET) and its downstream signaling proteins, such as p-AKT and p-ERK1/2

Accessed 12/1/2020, Formeister EJ, Rizk HG, Kohn MA, Sharon JD