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10.3389/fimmu.2023.1277554 74

Czysz AH, South C, Gadad BS, Arning E, Soyombo A, Bottiglieri T, et al

Sera from healthy donors yielded median MFI levels of 164 (range 501,235)

Multi-center, international trials will help account for genetic and environmental diversity

for example, the TLR4/NF-B/IL-1 signaling pathway is activated in chronic SZ patients (197), and clozapine reduces the expression of pro-inflammatory genes such as IL-1 and IL-6 by inhibiting the TLR4/NF-B pathway (198)