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Description

In obesity-related breast cancer murine models, the activation of STAT3 triggered an increase in FAO in CD8 + T cells, which suppressed glycolysis and weakened their tumor-suppressing ability

It is mainly used to screen for SDB in an outpatient setting

Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

& Cathers, B

Endpoint Assays for Mechanistic Insights The choice of assay depends on the specific pathway being investigated: Hormone Secretion: The amount of growth hormone released into the cell culture medium is quantified using a species-specific ELISA (Enzyme-Linked Immunosorbent Assay) kit