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In summary, the transient oxidative stress induced by ozone exposure activates the Nrf2 pathway, leading to the upregulation of genes involved in glutathione synthesis and an increase in intracellular glutathione levels

Curcumin (1015 mol/L) andCelecoxib (5 mol/L) at physiological dosages showed a synergistic inhibitory effect against human colon cancer (HT-29) cells [386]