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Hypoxia is a key regulator of metabolic plasticity, promoting adaptive responses such as the shift from oxidative to reductive glutamine metabolism, enhanced fatty acid oxidation, and lactate utilization

doi: 10.1186/s13048-024-01450-z

Decision curve analysis quantifying net benefit of predictive models with age stratification

During the transfer of electrons through a pathway, incomplete reduction of oxygen can result in the production of highly damaging and reactive ROS, such as hydroxyl radical, hydrogen peroxide, singlet oxygen and superoxide radicals The toxicity of superoxide radicals can be diminished with the help of metalloenzyme SOD which catalyzes the reduction of O 2 - to O 2 and H 2 O 2

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