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Preclinical data in glioblastomas showed that a single implant markedly reduced local recurrence and produced a median survival benefit, while pharmacokinetic studies showed therapeutic intraparenchymal temozolomide levels for over four weeks with minimal systemic exposure

The Xkr8 2DA (p.D351A&D354A) KI mice were generated via CRISPRCas9-mediated KI of the 2DA mutant cassette into exon 3 of Xkr8 gene (see Supplementary Fig

Role of non-coding RNAs in fungal pathogenesis and antifungal drug responses

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