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Fibrosis and Lipid Peroxidation : Fibrosis is characteristic of many tumours and may act as a mechanical barrier that prevents penetration of agents, including those aimed at lipid peroxidation

doi: 10.1016/j.bbrc.2017.10.088 155 ZhouRYazdiASMenuPTschoppJ

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Compounds may undergo fecal elimination if they were not absorbed in the intestine or were excreted from enterocytes back into the intestinal lumen via efflux transporters (73)