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Ciriolo, Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

Equal amounts of proteins (20 g) were subjected to SDS-PAGE and transferred to a 0.2 m PVDF membrane (Pall Life Science, USA)

Among the KRAS variants, the G13D mutation is associated with poor prognosis and distinctive biological behaviors

Glutathione, ascorbate and superoxide dismutase (SOD) are key components in plants (especially in plastids) for the detoxification of active oxygen species such as superoxide (O 2 - )