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10.1038/cdd.2016.134 12 BensaadK.TsurutaA.SelakM

They are framed in the guide the way they should be framed: as areas of preclinical research interest that the brand believes are relevant to its product, not as established human clinical outcomes

And in our "EPIC study's bluster about pimobendan unravels as critical analysis finally takes hold" , we noted that several cardiologists were rejecting the EPIC authors' recommendation to start pimobendan at the first sign of heart enlargement, and calling for a "more measured approach"