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The selective VDR agonist compound 15a has been shown to suppress collagen deposition and fibrosis-related gene expression in murine models of hepatic fibrosis, without inducing hypercalcemiaa common side effect observed with Calcipotriol or 1,25(OH) 2 D 3 (170)

Despite dicarboxylic acid and polar functional groups in its central moiety, CURs oilwater partition coefficient (logP) ranges between 2.3 and 2.6 [8]

reported that DZN induced oxidative stress in the brain, heart, and spleen of Wistar and Norway rats, with Wistar rats being more sensitive

Dopaminergic Neuronal Death in Substantia Nigra Associates with Serum Levels of Total Bilirubin, Selenium, and Zinc: Evidences from 6-Hydroxydopamine Animal Model of Parkinsons Disease